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Breakthrough in Cellular Defense

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Dab2 (red)-positive pre-adipocytes accumulating lipid droplets (green).

The Strange Double Life of Dab2 — the Cancer Protein that Also Plays a Role in Fat Storage

Sometimes proteins do a lot more than we expect. Dab2, for example, has long been linked to cancer. The molecule is associated with a chain of signaling proteins called the Ras-MAPK pathway. In many cancers, elements of Ras-MAPK mutate and start telling cells to grow uncontrollably.

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Michael Freundlich, M.D.

Researchers Uncover Mechanism for Vitamin D-Mediated Cardio-Protection in Kidney Insufficiency

Miller School of Medicine researchers have found that abnormal vitamin D status and elevated levels of the hormone FGF23 contribute to cardiac hypertrophy — a thickening of the heart muscle that may result in a decrease in size of the chamber of the heart and affect cardiac performance — in patients with chronic kidney disease.

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From left, Jonathan R. Wolpaw, M.D., W. Dalton Dietrich, Ph.D., Ozcan Ozdamar, Ph.D., and Daniel S. Rizzuto, Ph.D.

University of Miami Hosts First Neural Engineering Symposium

The University of Miami hosted its first Neural Engineering Symposium on October 13 to promote collaborations among research, educational, and industry programs for this rapidly growing discipline. Ozcan Ozdamar, Ph.D., professor and chair of the College of Engineering’s Department of Biomedical Engineering, and W. Dalton Dietrich, Ph.D., Scientific Director of The Miami Project to Cure Paralysis were Co-Directors.

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